| 产品详情 |
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| Product Name | GW-7647 |
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| Description | Purity >98% by HPLC. GW-7647 is a potent, selective agonist of human and murine PPARa. It activates human PPARa, PPARGamma, and PPARd with EC50 values of 0.006, 1.1 and 6.2 µM, respectively, in a GAL4-PPAR binding assay. Similar EC50 values of 0.001, 1.3, and 2.9 were observed with the murine receptors. Modulates oleate metabolism and mitochondrial enzyme gene expression in mature myotubules in vitro. Has lipid-lowering effects following oral administrationin vivo. Reduces NO production in macrophages; exhibits anti-inflammatory properties. A potent, selective agonist of human and murine PPARa. (Biochemical) |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[[4-[2-[[(Cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methylpropanoic acid |
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| Gene, Accession, CAS # | CAS: 265129-71-3 |
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| Catalog # | LS-H3598 |
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| Order / More Info | GW-7647 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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