| 产品详情 |
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| Product Name | Pep-1 (Uncapped) peptide |
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| Description | PEP-1 peptide, which has 21 amino acid residues, is a known carrier peptide that delivers full-length native proteins in vitro and in vivo. Pep-1 peptide, consists of three domains: (1) a hydrophobic tryptophan-rich motif containing five tryptophan residues (KETW WETWWTEW), (2) a hydrophilic lysine-rich domain (KKKRKV) derived from the nuclear localization sequence (NLS) of simian virus 40 (SV-40) large T antigen, and (3) a spacer domain (SQP), separating the two domains mentioned above, containing a proline residue, which improves the flexibility and the integrity of both the hydrophobic and the hydrophilic domains. In standard cell culture conditions, Pep-1 localizes rapidly, in <10 min, to the nucleus of human HS-68, murine NIH-3T3 fibroblasts, or Cos cells. Similar experiments, performed by incubating cells for 30 min at 4- before transfection, yielded essentially the same result, indicating that Pep-1 internalization is independent of normal endocytosis. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN399720 |
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| Price | |
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| Order / More Info | Pep-1 (Uncapped) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 18957395 |
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| 产品资料 |
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