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| Product Name | Recombinant Human TP53-regulated inhibitor of apoptosis 1 (TRIAP1) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 35.8kDa. Full Length: 1-76aa. N-terminal GST-tagged. Homo sapiens (Human). Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Protein 15E1.1; WF-1; p53-inducible cell-survival factor |
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| Gene, Accession, CAS # | TRIAP1, UniProt: O43715 |
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| Catalog # | RPC22173 |
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| Order / More Info | Recombinant Human TP53-regulated inhibitor of apoptosis 1 (TRIAP1) from BIOMATIK |
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| Product Specific References | n/a |
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