| 产品详情 |
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| Product Name | Diacerein |
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| Description | Purity >98%. Diacerein is a diacetyl precursor of rhein, an anthraquinone found in plants. Rhein, at 10 µM, inhibits IL-1Beta signaling, suppressing signaling through NF-?B and AP-1, and reduces the expression of the matrix metalloproteases MMP-1 and MMP-13. Diacerein, presumably after conversion to rhein, down-regulates the expression of the IL-1Beta receptor on articular chondrocytes, enhances the expression of TGF-Beta, and increases collagen and aggrecan. It does not alter COX activity. It is mildly effective in ameliorating osteoarthritis. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4,5-bis (acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid, 4,5-Diacetylrhein, DAR, SF 277 |
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| Gene, Accession, CAS # | CAS: 13739-02-1 |
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| Catalog # | LS-H7431 |
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| Price | |
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| Order / More Info | Diacerein from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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