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| Product Name | Recombinant Human SOSS complex subunit B2 (OBFC2A) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 38.4kDa. Full Length: 1-204aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Nucleic acid-binding protein 1Oligonucleotide/oligosaccharide-binding fold-containing protein 2ASensor of single-strand DNA complex subunit B2Sensor of ssDNA subunit B2; SOSS-B2Single-stranded DNA-binding protein 2; hSSB2 |
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| Gene, Accession, CAS # | NABP1, UniProt: Q96AH0 |
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| Catalog # | RPC23448 |
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| Price | |
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| Order / More Info | Recombinant Human SOSS complex subunit B2 (OBFC2A) from BIOMATIK |
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| Product Specific References | n/a |
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