产品详情 |
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Antigenic Specificity | AHNAK |
Clone | EM-09 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AHNAK Monoclonal Antibody (EM-09). AHNAK1 (Desmoyokin) is a large (700 kDa) scaffold protein that translocates to the plasma membrane after an increas of extracellular calcium level or upon proteinkinase C activation and regulates extracellular calcium influx mediated by L-type Ca2+ channels. AHNAK1 has been implicated in diverse signal transduction proceses affecting cell differentiation and proliferation. In response to calcium-dependent intercellular contacts AHNAK1 forms multimeric complexes in the plasma membrane, connected with actin and annexin 2/S100A10 assemblies and is thus involved in organization of the plasma membrane architecture. In epithelial cells, AHNAK1 is localized in cytoplasm or is membrane-associated, but in cells of |
Immunogen | n/a |
Other Names | AHNAKRS, MGC5395, AHNAK-related, desmoyokin, neuroblast differentiation-associated protein AHNAK |
Gene, Accession # | Entrez: 66395, 79026; Uniprot: Q09666 |
Catalog # | MA1-10050 |
Price | |
Order / More Info | AHNAK Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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