| 产品详情 |
| Edit |   |
|---|
| Product Name | MMP-3 Inhibitor VIII |
|---|
| Description | Purity >95%. Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 (also known as stromelysin-1) is thought to play a role in the vascular remodeling that occurs during aneurysm formation and may also be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII is a cell permeable sulfonamide-based hydroxamic acid that binds to the active site of MMP-3 (Ki = 23 nM) and prevents its activity. This compound has also been shown to inhibit mouse macrophage metalloelastase MME/MMP-12 with an IC50 value of 13 nM. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](phenylmethyl)amino]-4-methyl-pentanamide, Matrix Metalloproteinase-3 Inhibitor VIII, Stromelysin-1 Inhibitor VIII |
|---|
| Gene, Accession, CAS # | CAS: 208663-26-7 |
|---|
| Catalog # | LS-H8781 |
|---|
| Price | |
|---|
| Order / More Info | MMP-3 Inhibitor VIII from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|