| 产品详情 |
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| Product Name | Recombinant Human Ragulator complex protein LAMTOR3 (LAMTOR3) |
| Description | Purity > 90% as determined by SDS-PAGE. MW: 40.6kDa. Full Length: 1-124aa. N-terminal GST-tagged. Homo sapiens (Human). As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2. |
| Size | 100ug |
| Concentration | n/a |
| Applications | RUO |
| Other Names | Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 |
| Gene, Accession, CAS # | LAMTOR3, UniProt: Q9UHA4 |
| Catalog # | RPC21649 |
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| Order / More Info | Recombinant Human Ragulator complex protein LAMTOR3 (LAMTOR3) from BIOMATIK |
| Product Specific References | n/a |
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