| 产品详情 |
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| Product Name | UCM05 |
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| Description | Purity >95%. UCM05 is an inhibitor of fatty acid synthase that strongly suppresses the growth of human breast cancer cell lines (IC50 = 21 µM for SK-BR-3 cells). It does not alter carnitine palmitoyltransferase 1 activity or induce weight loss in mice. UCM05 can reduce cleavage of poly(ADP-ribose) polymerase, phosphorylation of HER2, Akt, and ERK1/2, and growth of established xenografts in vivo . UCM05 also blocks the GTP-binding site of the cell division protein FtsZ from Bacillus, preventing bacterial division. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3,4,5-trihydr3,4,5-trihydroxy-benzoic acid 1,1'-(1,3-naphthalenediyl) ester, G28UCM |
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| Gene, Accession, CAS # | CAS: 1094451-90-7 |
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| Catalog # | LS-H10354 |
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| Price | |
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| Order / More Info | UCM05 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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