| 产品详情 |
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| Product Name | Human SPR Protein (Recombinant His tag) |
| Description | Purity >95% by SDS-PAGE. Sepiapterin reductase (SPR) belongs to the short-chain dehydrogenase/reductase (SDR) family and also reduces various exogenous carbonyl compounds including phenylpropanedione. SPR is an essential enzyme for the biosynthesis of tetrahydrobiopterin, an essential cofactor for aromatic amino acid hydrolases including tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis. Defects in SPR cause DOPA-responsive dystonia defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Recombinant human SPR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | SPR, SDR38C1, Sepiapterin reductase |
| Gene, Accession, CAS # | SPR, Gene ID: 6697 |
| Catalog # | LS-G509 |
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| Order / More Info | Human SPR Protein (Recombinant His tag) from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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