| 产品详情 |
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| Product Name | SU-5416 |
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| Description | Purity >98% by HPLC. SU-5416 is a potent tyrosine kinase inhibitor best known as an inhibitor of the vascular endothelial growth factor receptor (VEGFR-2; Flk-1/KDR). In addition to inhibiting VEGFR-2 (IC50 = 1 MM), SU-5416 also inhibits PDGFR (IC50 = 20 MM), c-Kit (IC50 = 30 nM), RET (IC50 = 170 nM), Flt-3 (IC50 = 160 nM), ABL (IC50 = 11 MM), and ALK (IC50 = 1.2 MM).SU 5416 does not inhibit epidermal growth factor (EGFR) or fibroblast growth factor receptor (FGFR) tyrosine kinases (IC50 > 100 MM). Acts as a suppressor of tumor vascularization, preventing the growth of multiple tumor types. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Semaxinib, 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one |
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| Gene, Accession, CAS # | CAS: 204005-46-9 |
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| Catalog # | LS-H3539 |
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| Price | |
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| Order / More Info | SU-5416 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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