| 产品详情 |
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| Product Name | Triparanol |
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| Description | Purity >98%. Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 µM), which is an enzyme involved in the biosynthesis of cholesterol. It has antitumor properties, such as decreasing proliferation and inducing apoptosis in many cancer cell lines and slowing tumor growth in a mouse xenograft model. It can also decrease Hedgehog pathway signaling in cancer cells. Formulations containing triparanol were discontinued in the 1960s due to serious adverse side effects, including rapid cataract development. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-chloro-a-[4-[2-(diethylamino)ethoxy]phenyl]-a-(4-methylphenyl)-benzeneethanol, MER-29, NSC 65345 |
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| Gene, Accession, CAS # | CAS: 78-41-1 |
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| Catalog # | LS-H10318 |
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| Price | |
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| Order / More Info | Triparanol from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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