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| Product Name | Protocatechuic Acid |
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| Description | Purity >98%. Protocatechuic acid (PCA) is a dihydroxybenzoic acid phenolic compound found in many edible and medicinal plants. It is a major metabolite of antioxidant polyphenols found in green tea and demonstrates free radical scavenging capability in a 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity assay (IC50 = 16.3 µM). It is thought to possess anti-inflammatory, antihyperglycemic, neuroprotective, and anticancer activities. Dietary administration of PCA dose dependently inhibits in vitro chemical carcinogenesis and exerts pro-apoptotic and anti-proliferative effects in different tissues. In studies of tumor cell migration and invasion using mouse melanoma B16/F10 cells, PCA at 0.1-2 mM down-regulated the Ras/Akt/NF-?B pathway by targeting RhoB activation, leading to a reduction of MMP-mediated activity. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3,4-dihydroxy-benzoic acid, NSC 16631, PCA |
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| Gene, Accession, CAS # | CAS: 99-50-3 |
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| Catalog # | LS-H9524 |
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| Order / More Info | Protocatechuic Acid from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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