| 产品详情 |
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| Antigenic Specificity | Cytokeratin 5 |
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| Clone | EP1601Y |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | IgG |
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| Format | purified |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 1:100, Immunohistochemistry: 1:50, Western Blot: 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cytokeratin 5 Monoclonal Antibody (EP1601Y). Twenty human cytokeratins are divided into acidic (pI6.0) subfamilies. Members of the acidic and basic subfamilies are found together in pairs. The composition of cytokeratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of cytokeratins as markers in cancer research and tumor identification. Point mutations in cytokeratin-5 gene may cause Epidermolysis Bullosa Simplex and Dowling-Degos disease. cytokeratin-5 is expressed in most epithelioid and biphasic mesotheliomas, thymoma, squamous and other carcinomas. It is related to cytokeratin-6. |
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| Immunogen | n/a |
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| Other Names | 58 kda cytokeratin, CK-5, cytokeratin-5, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types), keratin, type II cytoskeletal 5, type-II keratin Kb5 |
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| Gene, Accession # | Entrez: 110308, 3852; Uniprot: P13647, Q922U2 |
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| Catalog # | MA5-14473 |
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| Price | |
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| Order / More Info | Cytokeratin 5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 21519545, 22040364, 22553347, 22689991, 23007879, 25383540, 26008846 |
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