产品详情 |
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Antigenic Specificity | Cytokeratin 8 |
Clone | 35bE11 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM |
Format | purified |
Size | 6 mL |
Concentration | n/a |
Applications | Immunohistochemistry (Frozen): Assay Dependent, Immunohistochemistry (Paraffin): Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cytokeratin 8 Monoclonal Antibody (35bE11). This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. |
Immunogen | n/a |
Other Names | CARD2, CK8, CYK8, K2C8, K8, KO |
Gene, Accession # | Entrez: 3856; Uniprot: P05787 |
Catalog # | MA1-26896 |
Price | |
Order / More Info | Cytokeratin 8 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 23683097 |
产品资料 |
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