| 产品详情 |
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| Product Name | BAY u3405 |
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| Description | Purity >98%. The biological effects of prostaglandin D2 (PGD2 ) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and DP2 /CRTH2. BAY u3405 (Ramatroban) is an approved human medication for the treatment of allergic rhinitis that has documented activity as an antagonist of the thromboxane receptor (TP receptor). BAY u3405 is also an antagonist of the DP2 receptor with IC50 values of 100-170 nM. BAY u3405 is more potent at the DP2 receptor than the TP receptor by 4-5 fold. BAY u3405 is therefore a useful tool for the elucidation of PGD2 /DP2 function in eosinophils, basophils, and other cells of the TH2 cell-type. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3R-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid, Ramatroban |
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| Gene, Accession, CAS # | CAS: 116649-85-5 |
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| Catalog # | LS-H6752 |
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| Order / More Info | BAY u3405 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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