Edit |   |
Antigenic Specificity | LYK5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 0.5-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LYK5 Polyclonal Antibody. Principal Names: LYK5; STE20-related Adaptor Protein (STRAD); FLJ90524; Official Gene Symbol: LYK5 Gene ID: 92335 (Human) Gene Map Locus: 17q23.3 (Human) Members of STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. STRAD is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and e |
Immunogen | n/a |
Other Names | STRAD |
Gene, Accession # | Entrez: 92335; Uniprot: Q7RTN6 |
Catalog # | PA1-41207 |
Price | |
Order / More Info | LYK5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |