| 产品详情 |
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| Product Name | DDMS |
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| Description | Purity >98%. Biosynthesis of 20-HETE from arachidonic acid by the cytochrome P450 4A (CYP450 4A) isoforms is an important component of vascular homeostasis, especially in renal circulation. DDMS is a mechanism-based, irreversible inhibitor that has about 10-fold selectivity for the CYP4A2 enzyme which predominantly synthesizes 20-HETE in the mammalian kidney. DDMS administration in whole anesthetized rats (10 mg/kg) largely ablates the hypotension and vasodilation induced by nitric oxide donors such as NONOates. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 12,12-dibromo-N-(methylsulfonyl)-11-dodecenamide, Dibromo-dodecenyl-methylsulfimide |
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| Gene, Accession, CAS # | CAS: 206052-03-1 |
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| Catalog # | LS-H7380 |
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| Price | |
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| Order / More Info | DDMS from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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