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| Product Name | IL2, Recombinant, Human (IL-2, T-Cell Growth Factor, TCGF, INN=Aldesleukin, Interleukin-2) |
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| Description | Purity ~95% (SDS-PAGE). IL-2 is produced mainly by T cells expressing the surface antigen CD4 following cell activation by mitogens or allogen. Interleukin-2 (IL-2) has multiple, sometimes opposing, functions during an inflammatory response. It is a potent inducer of T cell proliferation. Th1 and Th2 effector T cell differentiation and provides T cells with a long-lasting competitive advantage resulting in the optimal survival and function of memory cells. In a regulatory role, IL-2 is important for the development, survival, and function of regulatory T cells, it enhances Fas- mediated activation-induced cell death, and it inhibits the development of inflammatory Th17 cells. Thus, in its dual and contrasting functions, IL-2 contributes to both the induction and the termination of inflammatory immune responses. Source: Recombinant protein corresponding to human IL2 expressed in CHO cells. Molecular Weight: ~15kD Biological Activity: The ED50 was determined by the dose dependent proliferation of murine CTLL-2 |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P60568 |
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| Catalog # | 500129 |
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| Order / More Info | IL2, Recombinant, Human (IL-2, T-Cell Growth Factor, TCGF, INN=Aldesleukin, Interleukin-2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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