| 产品详情 |
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| Product Name | VEGFR2 Kinase Inhibitor II |
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| Description | Purity >95%. Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor II is a reversible, cell-permeable inhibitor of VEGFR2's kinase activity (IC50 = 70 nM). It less potently inhibits the platelet-derived growth factor receptor Beta (PDGFRBeta; IC50 = 920 nM) and related receptor and non-receptor tyrosine kinases. VEGFR2 kinase inhibitor II blocks the growth of human umbilical vein endothelial cells stimulated with either VEGF or PDGF (IC50 s = 110 nM and 2 µM, respectively). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (3Z)-5-bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-2H-indol-2-one |
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| Gene, Accession, CAS # | CAS: 288144-20-7 |
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| Catalog # | LS-H10418 |
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| Price | |
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| Order / More Info | VEGFR2 Kinase Inhibitor II from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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