| 产品详情 |
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| Antigenic Specificity | Lamin A/C |
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| Clone | 131C3 |
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| Host Species | Mouse |
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| Reactive Species | bovine, canine, hamster, human, mouse, ovine, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ChIP assay: 2.5 µg/10^6 cells, Flow Cytometry: 1:100-1:200, Immunocytochemistry: Assay dependent, Immunofluorescence: 1:100-1:200, Immunohistochemistry (Frozen): 1:100-1:200, Western Blot: 1:100-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Lamin A/C Monoclonal Antibody (131C3). Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial parti |
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| Immunogen | n/a |
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| Other Names | RP11-54H19.1, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, PRO1 |
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| Gene, Accession # | Entrez: 100757316, 101107924, 16905, 4000, 404144, 480124, 60374; Uniprot: P02545, P48678, P48679 |
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| Catalog # | MA1-06102 |
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| Price | |
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| Order / More Info | Lamin A/C Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 15623531, 27697922 |
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