| 产品详情 |
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| Antigenic Specificity | Lamin A/C |
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| Clone | 4E7 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Lamin A/C Monoclonal Antibody (4E7). The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Ma |
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| Immunogen | n/a |
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| Other Names | RP11-54H19.1, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1, 70 kDa lamin; lamin A/C-like 1; lamin-A/C; prelamin-A/C; renal carcinoma antigen NY-REN-32 |
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| Gene, Accession # | Entrez: 16905, 4000, 60374; Uniprot: P02545, P48678, P48679 |
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| Catalog # | MA5-15882 |
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| Price | |
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| Order / More Info | Lamin A/C Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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