| 产品详情 |
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| Antigenic Specificity | Lamin A/C |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Lamin A/C Polyclonal Antibody. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, |
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| Immunogen | n/a |
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| Other Names | CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1, LMNA, renal carcinoma antigen NY-REN-32, lamin A/C-like 1, prelamin-A/C, 70 kDa lamin, lamin A/C |
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| Gene, Accession # | Entrez: 16905, 4000, 60374; Uniprot: P02545, P48678, P48679 |
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| Catalog # | PA5-78042 |
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| Price | |
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| Order / More Info | Lamin A/C Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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