| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | MB67 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | bovine, canine, guinea pig, human, mouse, porcine, rat |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry: 5 µg/mL, Western Blot: 1.25 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | MB67 Polyclonal Antibody. This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid |
|---|
| Immunogen | n/a |
|---|
| Other Names | Nuclear receptor subfamily 1, group I member 3, CAR, CAR1, MB67, MGC150433, MGC97144, MGC97209 |
|---|
| Gene, Accession # | Entrez: 100714102, 12355, 488653, 493711, 65035, 654317, 9970; Uniprot: O35627, Q14994, Q9QUS1 |
|---|
| Catalog # | PA5-42748 |
|---|
| Price | |
|---|
| Order / More Info | MB67 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|