| 产品详情 |
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| Product Name | SMI-4a |
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| Description | Purity >98% by NMR, TLC. SMI-4a is a selective, ATP-competitive inhibitor of the Pim protein kinases (IC50 = 24 and 100 nM for Pim-1 and Pim-2 respectively). Selective over a panel of ~50 other kinases. Induces cell cycle arrest in leukemia and prostate cancer cells. Blocks the growth of a wide range of myeloid and lymphoid cell lines with precursor T-cell lymphoblastic leukemia/lymphoma (pre-T-LBL/T-ALL) being highly sensitive. SMI-4a is a useful tool for exploring the involvement of Pim in cellular signaling. Cell permeable. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-(3-Trifluoromethylbenzylidene)thiazolidine |
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| Gene, Accession, CAS # | CAS: 438190-29-5 |
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| Catalog # | LS-H14508 |
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| Order / More Info | SMI-4a from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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