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| Product Name | Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) (Active) protein |
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| Description | Chemokine (C-C motif) ligand 5(CCL5), also known as RANTES (Regulated upon activation, Normal T cell Expressed and presumable Secreted) is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. RANTES is chemotactic for T cells, eosinophils, and basophils, and plays an active role in recruiting leukocytes in inflammatory sites. With the help of specific cytokines (i.e., IL-2 and IFN-gamma) that are released by T cells, RANTES induces the proliferation and activation of certain natural-killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells. RANTES is also an HIV-suppressive factor released from CD8+ T cells. This chemokine has been localized to chromosome 17 in humans. It has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV).Recombinant human RANTES/CCL5 produced in HEK293 cells is a single polypeptide chain containing 68 amino acids. A fully biologically active molecule, rhRANTES/CCL5 has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE. Synonyms: RANTES/CCL5, Human |
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| Size | 5 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Rantes|Scya5|D17S136E|RANTES|SCYA5|SIS-delta|SISd|TCP228|eoCP|MuRantes |
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| Gene, Accession, CAS # | Gene ID: 6352 |
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| Catalog # | ABIN2018333 |
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| Order / More Info | Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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