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| Product Name | Chemokine (C-C Motif) Ligand 8 (CCL8) (AA 24-99) (Active) protein |
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| Description | MCP-2 is a member of the chemokines, a group of 70-80 residue proteins sharing substantial sequence similarity. Within the chemokines, MCP-2 belongs to the CC subfamily, and is a member of the Monocyte Chemoattractant Proteins (MCPs), which includes MCP-1, MCP-2, MCP-3, MCP-4, and MCP-5. MCP-2 shares 60% homology with MCP-1, and both proteins can undergo reversible dimerization. The main receptors of MCP-2 are G-protein coupled receptors CCR1 and CCR5. MCP-2 is a potential target in HIV-1 infected human glial cells as it may play a role in the modulation of viral spread in the brain. Recently, researchers found that mouse MCP-2 is expressed in the skin as a novel agonist of CCR8 and plays a role in eosinophilic inflammation.Recombinant human MCP-2/CCL8(rhMCP-2) produced in E. coli is a single non-glycosylated polypeptide chain containing 76 amino acids. A fully biologically active molecule, rhMCP-2 has a molecular mass of 8.9kDa analyzed by reducing SDS-PAGE. Synonyms: Monocyte Chemoattractant Protein-2, HC14, SCYA8 |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HC14|MCP-2|MCP2|SCYA10|SCYA8|1810063B20Rik|AB023418|Mcp2|Scya8 |
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| Gene, Accession, CAS # | Gene ID: 6355 |
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| Catalog # | ABIN2018230 |
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| Order / More Info | Chemokine (C-C Motif) Ligand 8 (CCL8) (AA 24-99) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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