产品详情 |
Edit |   |
Product Name | Chemokine (C-C Motif) Ligand 15 (CCL15) (AA 22-113), (Ile24Thr-Mutant) (Active) protein |
Description | Macrophage Inflammatory Protein-5 (MIP-5/CCL15) is a chemokine originally identified in the human hemofiltrate, thus it is also named Hemofiltrate CC Chemokine-2 (HCC-2). MIP-5 belongs to the CCL chemokine family, and its receptors are G-protein coupled receptors CCR1 and CCR3, with CCR1 being the major one. MIP-5 is mainly expressed in heart and skeletal muscle, and CCR1 is expressed on Th1 and Th2 cells in human cord blood lymphocytes. In vivo, MIP-5 promotes the accumulation of immature myeloid cells and the expansion of metastatic foci in the lever. MIP-5 contributes to severe asthma, sarcoidosis, and atherosclerosis,however, MIP-5 can also inhibit stem cell proliferation, implicating its therapeutic potential as an alternative to high dose chemotherapy.Recombinant human MIP-5/CCL15 (rhMIP-5/CCL15) produced in E.coli is a single non-glycosylated polypeptide chain containing 92 amino acids. A fully biologically active molecule, rhMIP-5/CCL15 has a molecular mass of 10.2 kDa analyzed by reducing SDS-PAGE. Synonyms: HCC-2, LKN-1, MIP-1 delta |
Size | 5 µg |
Concentration | n/a |
Applications | n/a |
Other Names | HCC-2|HMRP-2B|LKN-1|LKN1|MIP-1 delta|MIP-1D|MIP-5|MRP-2B|NCC-3|NCC3|SCYA15|SCYL3|SY15 |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN2018261 |
Price | |
Order / More Info | Chemokine (C-C Motif) Ligand 15 (CCL15) (AA 22-113), (Ile24Thr-Mutant) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
产品资料 |
|
|