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| Product Name | Chemokine (C-C Motif) Ligand 26 (CCL26) (AA 24-94) protein |
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| Description | Chemokine Ligand 26 protein (CCL26) is a novel small cytokine belonging to the CC chemokine family which is involved in immunoregulatory and inflammatory processes. CCL26 is constitutively expressed in thymus, but only transiently expressed in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for CCL26 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant CCL26 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, CCL26 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. CCL26 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.Alternative Names: C-C Motif Chemokine 26, CC Chemokine IMAC, Eotaxin-3, Macrophage Inflammatory Protein 4-Alpha, MIP-4-Alpha, Small-Inducible Cytokine A26, Thymic Stroma Chemokine-1, TSC-1, CCL26, SCYA26 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CCL26|IMAC|MIP-4a|MIP-4alpha|SCYA26|TSC-1|Ccl26l |
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| Gene, Accession, CAS # | Gene ID: 10344 |
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| Catalog # | ABIN1096267 |
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| Order / More Info | Chemokine (C-C Motif) Ligand 26 (CCL26) (AA 24-94) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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