| 产品详情 |
| Edit |   |
|---|
| Product Name | Interleukin 17A (IL17A) (Active) protein |
|---|
| Description | Recombinant Human Interleukin-17A/IL-17A produced in E. coli is a single non-glycosylated polypeptide chain containing 133 AAs with a molecular mass of 15,256 Daltons. Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-α, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation. |
|---|
| Size | 1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Il17|IL17A|CTLA8|IL-17|IL-17A|IL17|Ctla-8|Ctla8|CTLA-8|ChIL-17|IL-17F |
|---|
| Gene, Accession, CAS # | Gene ID: 3605 |
|---|
| Catalog # | ABIN1096904 |
|---|
| Price | |
|---|
| Order / More Info | Interleukin 17A (IL17A) (Active) protein from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|