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| Product Name | Interleukin 17A (IL17A) (Active) protein |
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| Description | Recombinant Human Interleukin-17A/IL-17A produced in E. coli is a single non-glycosylated polypeptide chain containing 133 AAs with a molecular mass of 15,256 Daltons. Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-α, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation. |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Il17|IL17A|CTLA8|IL-17|IL-17A|IL17|Ctla-8|Ctla8|CTLA-8|ChIL-17|IL-17F |
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| Gene, Accession, CAS # | Gene ID: 3605 |
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| Catalog # | ABIN1690796 |
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| Price | |
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| Order / More Info | Interleukin 17A (IL17A) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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