| 产品详情 |
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| Antigenic Specificity | UBQLN4/CIP75/Ubiquilin 4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | UBQLN4/CIP75/Ubiquilin 4 Polyclonal Antibody. The ubiquitin-proteosome pathway of protein degradation is one of the mechanisms that ensure the proper level of cellular proteins. The ubiquitin-like (UbL) and ubiquitin-associated (UBA) domain containing protein family is thought to be involved in proteosomal degradation. One such protein is CIP75, also known as ubiquilin-4, interacts with a number of proteins such as Ataxin-1 and Connexin-43, resulting in an increased rate of turnover of these proteins. Overexpression CIP75 led to a significant reduction of Connexin-43 half-life, with the opposite being observed in siRNA knockdown experiments. CIP75 contains an N-terminal UbL domain which is thought to interact with proteins of the 26S proteo |
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| Immunogen | n/a |
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| Other Names | RP11-336K24.8, A1U, C1orf6, CIP75, UBIN; ataxin-1 ubiquitin-like interacting protein; ataxin-1 ubiquitin-like-interacting protein A1U; ubiquilin-4 |
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| Gene, Accession # | Entrez: 56893; Uniprot: Q9NRR5 |
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| Catalog # | A305-237A |
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| Price | |
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| Order / More Info | UBQLN4/CIP75/Ubiquilin 4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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