产品详情 |
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Antigenic Specificity | IRGC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 5 µg/mL, Immunofluorescence: 20 µg/mL, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IRGC Polyclonal Antibody. Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates, which play critical roles in mediating innate resistance to intracellular pathogens. IRG genes have been found in a number of mammals and lower species including mice, rats, zebrafish and humans. Most of the mouse genes contain interferon-stimulated response elements which mediate transcriptional activation by IFNs. In humans, only two IRG genes have been found: human IRGC encodes a full-length IRG protein that, like the mouse homologue, is constitutively expressed in testis, while human IRGM encodes a considerably truncated protein that is constitutively expressed in cultured cells including some macrop |
Immunogen | n/a |
Other Names | CINEMA, IRGC1, Iigp5, R30953_1; immunity-related GTPase cinema 1; immunity-related GTPase family, cinema 1; interferon inducible GTPase 5; interferon-inducible GTPase 5 |
Gene, Accession # | Entrez: 210145, 308428, 56269; Uniprot: Q6AYF9, Q6NXR0, Q8C262 |
Catalog # | PA5-20789 |
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Order / More Info | IRGC Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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