产品详情 |
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Antigenic Specificity | Pannexin 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 50 µl |
Concentration | lyophilized |
Applications | Immunofluorescence: 1:300, Immunohistochemistry: 1:300, Western Blot: 1:400 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Pannexin 1 Polyclonal Antibody. The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation. |
Immunogen | n/a |
Other Names | Pannexin 1 |
Gene, Accession # | Entrez: 24145, 315435, 55991; Uniprot: P60570, Q96RD7, Q9JIP4 |
Catalog # | PA5-77358 |
Price | |
Order / More Info | Pannexin 1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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