产品详情 |
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Antigenic Specificity | Pannexin 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Pannexin 1 Polyclonal Antibody. Pannexin 1 is part of the pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation. |
Immunogen | n/a |
Other Names | PX1, UNQ2529, MRS1, pannexin 1, PANX1 |
Gene, Accession # | Entrez: 24145; Uniprot: Q96RD7 |
Catalog # | PA5-78455 |
Price | |
Order / More Info | Pannexin 1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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