产品详情 |
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Product Name | Dimebolin dihydrochloride |
Description | Purity >99% by HPLC Heavy Metals: Less than 20 ppm . A Histamine H1 receptor antagonist. It has been used clinically in Russia as antihistaminergic drug since 1983. Recently it has been shown to inhibit brain cell death in preclinical studies of Alzheimer's disease and Huntington's disease, making it a potential treatment for these and other neurodegenerative diseases. It appears to operate through multiple mechanisms of action, e.g. blocking the action of neurotoxic Beta-Amyloid proteins, inhibiting L-type calcium channels and modulating the action of AMPA and NMDA Glutamate receptors. It acts also as a 5-HT6 receptor antagonist (Ki = 26 nM). |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | 2,3,4,5-Tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)ethyl)-1H-pyrido (4,3-b)indole dihydrochloride, Dimebon, Latrepirdine |
Gene, Accession, CAS # | CAS: 97657-92-6 |
Catalog # | LS-H12350 |
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Order / More Info | Dimebolin dihydrochloride from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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