产品名称 Dimebolin dihydrochloride from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H12350
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameDimebolin dihydrochloride
DescriptionPurity >99% by HPLC Heavy Metals: Less than 20 ppm . A Histamine H1 receptor antagonist. It has been used clinically in Russia as antihistaminergic drug since 1983. Recently it has been shown to inhibit brain cell death in preclinical studies of Alzheimer's disease and Huntington's disease, making it a potential treatment for these and other neurodegenerative diseases. It appears to operate through multiple mechanisms of action, e.g. blocking the action of neurotoxic Beta-Amyloid proteins, inhibiting L-type calcium channels and modulating the action of AMPA and NMDA Glutamate receptors. It acts also as a 5-HT6 receptor antagonist (Ki = 26 nM).
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Other Names2,3,4,5-Tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)ethyl)-1H-pyrido (4,3-b)indole dihydrochloride, Dimebon, Latrepirdine
Gene, Accession, CAS #CAS: 97657-92-6
Catalog #LS-H12350
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Order / More InfoDimebolin dihydrochloride from LIFESPAN BIOSCIENCES INC.
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