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| Product Name | PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (ammonium salt) |
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| Description | Purity >98%. The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2 incorporated into membrane lipids can bind to important proteins such as Group IV cPLA2 and PLCDelta1, enhancing their adherence to the membrane and increasing the rate of substrate hydrolysis. PtdIns-(4,5)-P2 can be further phosphorylated to give triphosphates such as PtdIns-(3,4,5)-P3 . It can also be cleaved by PI-specific PLC to give inositol triphosphates. The diacyl glycerol and IP3 generated by this PLC-cleavage are also part of a complex biochemical and signal transduction cascade which has not been entirely elucidated. For some additional reading, please see references 2, 4, and 5 . |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-(1,2R-dihexadecanoylphosphatidyl)inositol-4,5-bisphosphate, triammonium salt, DPPI-4,5-P2, Phosphatidylinositol-4,5-diphosphate C-16 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H9571 |
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| Order / More Info | PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (ammonium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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