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| Product Name | PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) |
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| Description | Purity >98%. The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin Alpha and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3 -binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references 5 and 6 . |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | D-myo -inositol 1-[(2R)-2,3-bis [(1-oxohexadecyl)oxy]propyl hydrogen phosphate] 3,4,5-tris (dihydrogen phosphate), tetrasodium salt, DPPI-3,4,5-P3, Phosphatidylinositol-3,4,5-triphosphate C-16 |
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| Gene, Accession, CAS # | CAS: 1628353-02-5 |
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| Catalog # | LS-H9555 |
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| Order / More Info | PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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