| 产品详情 |
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| Antigenic Specificity | ELL3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ELL3 Polyclonal Antibody. Enhancer-binding elongation factor that specifically binds enhancers in embryonic stem cells (ES cells), marks them, and is required for their future activation during stem cell specification. Does not only bind to enhancer regions of active genes, but also marks the enhancers that are in a poised or inactive state in ES cells and is required for establishing proper RNA polymerase II occupancy at developmentally regulated genes in a cohesin-dependent manner. Probably required for priming developmentally regulated genes for later recruitment of the super elongation complex (SEC), for transcriptional activation during differentiation. Required for recruitment of P-TEFb within SEC during differentiation. Probably prel |
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| Immunogen | n/a |
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| Other Names | RNA polymerase II elongation factor ELL3, ELL3 |
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| Gene, Accession # | Entrez: 80237; Uniprot: Q9HB65 |
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| Catalog # | PA5-48984 |
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| Price | |
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| Order / More Info | ELL3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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