| 产品详情 |
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| Antigenic Specificity | CD134 (OX40) |
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| Clone | ACT35 (ACT-35) |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1 µg/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD134 (OX40) Monoclonal Antibody (ACT35 (ACT-35)), eBioscience™. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
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| Immunogen | n/a |
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| Other Names | cluster designation 134, TNFRSF4 |
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| Gene, Accession # | Entrez: 7293; Uniprot: P43489 |
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| Catalog # | 14-1347-82 |
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| Price | |
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| Order / More Info | CD134 (OX40) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 24771328, 27141370, 27756099 |
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