| 产品详情 |
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| Antigenic Specificity | CD134 (OX40) |
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| Clone | OX-86 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1, kappa |
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| Format | unconjugated, functional grade |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD134 (OX40) Monoclonal Antibody (OX-86), Functional Grade, eBioscience™. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
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| Immunogen | n/a |
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| Other Names | cluster designation 134, TNFRSF4 |
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| Gene, Accession # | Entrez: 22163; Uniprot: P47741 |
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| Catalog # | 16-1341-85 |
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| Price | |
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| Order / More Info | CD134 (OX40) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 15126371, 21491419, 24220301, 24633226, 24752446, 27043411, 28696253, 9886424 |
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