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Antigenic Specificity | PI3 kinase p85 alpha subunit |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB, FCM, IHC-P, IF(IHC-P), IF(ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PI3 kinase p85 alpha subunit Antibody. • Target Background: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. |
Immunogen | KLH conjugated synthetic peptide derived from human PI3 kinase p85 subunit alpha . Immunogen Range: 530-580/724 |
Other Names | p85; AGM7; GRB1; IMD36; p85-ALPHA; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha; PIK3R1 |
Gene, Accession # | Gene ID: 5295, SwissProt: P27986 |
Catalog # | bs-0128R |
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Order / More Info | PI3 kinase p85 alpha subunit Antibody from BIOSS ANTIBODIES |
Product Specific References | Xu, H. et al (2013) BMC cancer 13.1 247. PubMed: 23688241 // Sun, Yan, et al. (2014) Theriogenology. PubMed: 25284282 // Xu, C., et al .(2014) J Proteomics Computational Biol. PubMed: not posted yet // An, Xinjiang, et al.(2016) Exp Ther Med. 11.4:1318-1322. PubMed: 27073442 // Tian, L-Y., et al. (2010) Phytomedicine. 17.7:533-539. PubMed: 19962285 // Bai, Xue, et al. (2009) J Ethnopharmacol. 125.3:482-486. PubMed: 19607904 // Wang, Fan, et al. (2017) Mol Med Rep. PubMed: 28990055 // Wang, Fan, et al. (2017) Mol Med Rep. PubMed: 28990055 // Yang et al. (2014) Exp.Ther.Me. 8:563-566. PubMed: 25009620 |
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