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| Product Name | Human CXCL11 Protein (Recombinant) |
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| Description | Purity >98% by SDS-PAGE, MW: 8.3 kDa (SDS-PAGE). Chemokine (C-X-C motif) ligand 11(CXCL11), also known as I-TAC and B-R1, is a small cytokine belonging to the CXC chemokine family that is also called Interferon-inducible T-cell alpha chemoattractant (I-TAC) and Interferon-gamma-inducible protein 9 (IP-9).This chemokine elicits its effects on target cells by interacting with chemokine receptor CXCR3 having a higher affinity than other ligands for this receptor such as CXCL9 and CXCL10. CXCL11 is chemotactic for activated T cells. The gene encoding CXCL11 has been mapped to chromosome 4. CXCL11 cDNA encodes a 94 amino acid residue precursor protein with a 21 amino acid residue putative signal sequence, which is cleaved to form the mature 73 amino acid residue protein. CXCL11 shares 36% and 37% amino acid sequence homology with IP-10 and MIG (two other known human non-ELR CXC chemokines), respectively. Mouse CXCL11 exhibits 68% sequence homology with human CXCL11. Recombinant human I-TAC/CXCL11 produced in HEK293 cells is a single non-glycosylated polypeptide chain containing 73amino acids. A fully biologically active molecule, rhI-TAC/CXCL11 has a molecular mass of 8.3 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CXCL11, Beta-R1, Chemokine h174, Chemokine ip-9, Chemokine itac, H174, I-TAC, IP9, ITAC, IP-9, SCYB11, Small inducible cytokine B11, B-R1, C-X-C motif chemokine 11, SCYB9B, Small-inducible cytokine B11 |
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| Gene, Accession, CAS # | CXCL11, Gene ID: 6373 |
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| Catalog # | LS-G27111 |
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| Price | |
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| Order / More Info | Human CXCL11 Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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