产品详情 |
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Product Name | Fenretinide |
Description | Purity >98% by HPLC Heavy Metals: Less than 20 ppm . Synthetic retinoid agonist and potent anticancer agent. Apoptotic effects appear to be mediated to an increase in intracellular levels of ceramide, which is subsequently metabolized to GD3. This ganglioside triggers the activation of 12-Lox (12-Lipoxygenase) leading to oxidative stress and apoptosis via the induction of the transcription factor Gadd153 and the Bcl-2-family member protein Bak. Also displays antiproliferative and antioxidant effects. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenamide (2E,4E,6E,8E)-N-(4-Hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenamide, 4-HPR |
Gene, Accession, CAS # | CAS: 65646-68-6 |
Catalog # | LS-H11222 |
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Order / More Info | Fenretinide from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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