产品详情 |
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Antigenic Specificity | CCL7 (MCP3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | ELISA: Assay-dependent, Western Blot: 0.5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCL7 (MCP3) Polyclonal Antibody. Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, MCP3 gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response. |
Immunogen | n/a |
Other Names | C-C motif chemokine 7, Intercrine/chemokine MARC, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, MCP-3, Protein FIC, Small-inducible cytokine A7, Ccl7, Fic, Mcp3, Scya7 |
Gene, Accession # | Entrez: 20306; Uniprot: Q03366 |
Catalog # | PA5-78940 |
Price | |
Order / More Info | CCL7 (MCP3) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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