| 产品详情 |
| Edit |   |
|---|
| Product Name | Fenofibric Acid |
|---|
| Description | Purity >98%. Fenofibric acid is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides. It displays high affinity for liver fatty acid binding protein (Ki = 24 nM). Fenofibric acid increases plasma apolipoprotein A-II via the response element for peroxisome proliferator-activated receptors (PPARs), although it has very low affinity for PPARs (IC50 s > 100 µM for both human PPARAlpha or PPARGamma). However, in a transactivation assay, it exhibits EC50 values of 18 and 30 µM for mosue and human PPARAlpha, respectively. Fenofibric acid, when combined with statins, has been shown to be effective against mixed dyslipidemia in clinical trials. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid, FNF Acid, NSC 281318 |
|---|
| Gene, Accession, CAS # | CAS: 42017-89-0 |
|---|
| Catalog # | LS-H7768 |
|---|
| Price | |
|---|
| Order / More Info | Fenofibric Acid from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|