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Product Name | 7-Azido-4-methylcoumarin |
Description | Purity >98% by HPLC. 7-Azido-4-methylcoumarin is a highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. It is a photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). 7-Azido-4-methylcoumarin is a tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)) and to identify novel cystathionine beta-synthase (CBS) inhibitors and activators. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | 7-Azido-4-methyl-1-benzopyran-2-one, AzMC |
Gene, Accession, CAS # | CAS: 95633-27-5 |
Catalog # | LS-H869 |
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Order / More Info | 7-Azido-4-methylcoumarin from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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