| 产品详情 |
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| Product Name | ARN14974 |
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| Description | Purity >98%. ARN14974 is a benzoxazolone carboxamide that potently inhibits acid ceramidase (IC50 = 79 nM). This effect is persistent, as it inhibits acid ceramidase activity in cells for up to 24 hours. ARN14974 is extremely stable in buffers and plasma and shows good pharmacokinetics when administered intravenously or intraperitoneally in mice. It causes a significant reduction in acid ceramidase activity in multiple organs in mice, including brain, liver, heart, lungs, and kidney. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-(4-fluorophenyl)-2-oxo-N-(4-phenylbutyl)-3(2H)-benzoxazolecarboxamide, Acid Ceramidase Inhibitor 17a |
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| Gene, Accession, CAS # | CAS: 1644158-57-5 |
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| Catalog # | LS-H6616 |
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| Price | |
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| Order / More Info | ARN14974 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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