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| Product Name | ARN-509 |
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| Description | Purity >98%. ARN-509 is an antagonist of the androgen receptor (IC50 = 16 nM). It binds the receptor but does not cause nuclear localization or DNA binding. ARN-509 is orally bioavailable and, at 30 mg/kg/d, suppresses tumor growth in a mouse model of castration-resistant prostate cancer. This compound can be used to study androgen signaling in vitro and in vivo and has potential applications in certain types of cancer. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methyl-benzamide, JNJ-56021927 |
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| Gene, Accession, CAS # | CAS: 956104-40-8 |
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| Catalog # | LS-H6617 |
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| Order / More Info | ARN-509 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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