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| Product Name | Anisomycin |
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| Description | Purity >98%. Anisomycin is a pyrrolidine antibiotic produced by S. griseolus that inhibits protein and DNA synthesis. It activates stress-activated protein kinase, MAP kinase, and other signal transduction pathways. At 30 mg/kg, anisomycin displays immunosuppressive activity superior to that of Cyclosporine A, blocking T cell proliferation in skin-transplanted mice. Through a caspase-8-dependent pathway, anisomycin acts as a potent and specific anoikis sensitizer of malignant epithelial cells resistant to apoptosis upon detachment from the ECM, preventing distal tumor formation in a mouse model of prostate cancer metastases. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[(4-methoxyphenyl)methyl]-3-acetate-(2R,3S,4S)-3,4-pyrrolidinediol, Flagecidin, NSC 76712, Wuningmeisu C |
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| Gene, Accession, CAS # | CAS: 22862-76-6 |
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| Catalog # | LS-H6553 |
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| Order / More Info | Anisomycin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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